854931-43-4

Basic information

• Product Name: trans-(1S,3R)-(-)-2-benzyl-3-ethoxycarbonyl-7-methoxy-1-methoxycarbonylethyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
• Synonyms: trans-(1S,3R)-(-)-2-benzyl-3-ethoxycarbonyl-7-methoxy-1-methoxycarbonylethyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
• CAS NO: 854931-43-4
• Molecular Weight: 450.535
• Mol File: 854931-43-4.mol

Chemical Properties

• CAS DataBase Reference: trans-(1S,3R)-(-)-2-benzyl-3-ethoxycarbonyl-7-methoxy-1-methoxycarbonylethyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole(CAS DataBase Reference)
• NIST Chemistry Reference: trans-(1S,3R)-(-)-2-benzyl-3-ethoxycarbonyl-7-methoxy-1-methoxycarbonylethyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole(854931-43-4)
• EPA Substance Registry System: trans-(1S,3R)-(-)-2-benzyl-3-ethoxycarbonyl-7-methoxy-1-methoxycarbonylethyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole(854931-43-4)

Safety Data

• Hazardous Substances Data: 854931-43-4(Hazardous Substances Data)

Upstream product

• 355840-03-8 6-methoxy-D-tryptophan ethyl ester 
• 100-52-7 benzaldehyde 
• 919282-26-1 cis-(1R,3R)-(-)-2-benzyl-3-ethoxycarbonyl-7-methoxy-1-methoxycarbonylethyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole 
• 854931-42-3 2-benzylamino-3-(6-methoxy-1H-indol-3-yl)-propionic acid ethyl ester 
• 13865-19-5 4-oxobutanoic acid methyl ester 

Downstream Products

• 23172-98-7 gardnutine 
• 23172-92-1 gardnerine 
• 854931-44-5 C₂₂H₂₂N₂O₂ 

Relevant articles and documents

Conformational analysis of the cis- and trans-adducts of the Pictet-Spengler reaction. Evidence for the structural basis for the C(1)-N(2) scission process in the cis- to trans-isomerization

The stable conformations of both the trans- and cis-1,3-disubstituted Nb-benzyl stereoisomers of the Pictet-Spengler reaction have been determined by NMR spectroscopy and X-ray crystallography in order to better understand the C(1)-N(2) cis- to

First regiospecific, enantiospecific total synthesis of gardnerine and gardnutine

The first enantiospecific total synthesis of gardnerine and gardnutine has been achieved from 6-methoxy-d-tryptophan via the asymmetric Pictet-Spengler reaction, a stereocontrolled intramolecular enolate driven palladium-mediated cross-coupling reaction a