854934-97-7Relevant academic research and scientific papers
NOVEL AZABICYCLIC ARYL DERIVATIVES AND THEIR MEDICAL USE
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Page/Page column 16, (2008/06/13)
This invention relates to novel azabicyclic aryl derivatives of formula (I), which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profil
Fused bicycloheterocycle substituted quinuclidine derivatives
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, (2008/06/13)
Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N+—O—; X is O, S, —NH—, and —N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
