854948-76-8Relevant academic research and scientific papers
Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1, 3-diones as potent caspase-3 inhibitors
Kravchenko, Dmitri V.,Kuzovkova, Yulia A.,Kysil, Volodymyr M.,Tkachenko, Sergey E.,Maliarchouk, Sergey,Okun, Ilya M.,Balakin, Konstantin V.,Ivachtchenko, Alexandre V.
, p. 3680 - 3683 (2007/10/03)
Synthesis, biological evaluation, and SAR dependencies for a series of novel 1,3-dioxo-2,3-dihydro-1H-pyrrolo-[3,4-c]quinoline inhibitors of caspase-3 are described. The inhibitory activity of the synthesized compounds is highly dependent on the nature of
