85518-80-5

Upstream product

• 110-46-3 isopentyl nitrite 
• 87-62-7 2,6-dimethylaniline 

Downstream Products

• 118-72-9 2,6-dimethylbenzene-1-thiol 
• 27969-93-3 1-(2,6-Dimethyl-phenylazo)-[2]naphthol 
• 603-77-0 (2,6-dimethylphenyl)hydrazine 
• 54088-93-6 2,6-dimethylphenyl phenyl sulfide 
• 71258-85-0 2-(2,6-dimethyl-phenylhydrazono)-propionic acid ethyl ester 
• 2538-61-6 (2,6-dimethylphenyl)hydrazine monohydrochloride 
• 96406-73-4 N-(5,6-Dihydro-4H-[1,3]thiazin-2-yl)-N'-(2,6-dimethyl-phenyl)-hydrazine; hydrochloride 
• 96423-54-0 N-(4,5-Dihydro-thiazol-2-yl)-N'-(2,6-dimethyl-phenyl)-hydrazine; hydrobromide 
• 104216-45-7 3-(2,6-dimethylphenylsulfanyl)-propanoic acid 
• 2905-17-1 bis(2,6-dimethylphenyl)disulfide 

Relevant academic research and scientific papers

Heteroarylaminopyrazole derivatives useful for the treatment of diabetes

The present invention relates to heteroarylaminopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.

Antiimplantation Agents: Part I - 1-Arylthiosemicarbazides

Several 1-arylthiosemicarbazides, 2-arylhydrazinothiazolines and 2-arylhydrazinodihydrothiazines have been examined for their antiimplantation activity in rats.Among the active compounds, 4-methyl-1-(3,5-bistrifluoromethylphenyl)thiosemicarbazide (3, C 2696-Go) and the corresponding 4,4-dimethyl (47), ethyl (4), n-butyl (5) and allyl (6) derivatives completely inhibit implantation at doses 10, 3, 20, 20 and 30 mg/kg respectively.The 3,4-dichlorophenyl analogue (32) is effective at a dose of 30 mg/kg. 2-(3,5-Bistrifluoromethylphenyl)hydrazinothiazoline (51) and the corresponding dihydrothiazine (63) show a weaker activity.The biological profile of C 2696-Go has been investigated in detail.It appears to prevent implantation by its antiuterotropic activity and ability to inhibit desiduoma formation.