855199-30-3Relevant academic research and scientific papers
Nickel-catalysed cross-electrophile coupling of aryl bromides and primary alkyl bromides
Gao, Nanxing,Li, Yanshun,Teng, Dawei
, p. 3569 - 3572 (2022/02/11)
The structure of primary alkylated arenes plays an important role in the molecular action of drugs and natural products. The nickel/spiro-bidentate-pyox catalysed cross-electrophile coupling of aryl bromides and primary alkyl bromides was developed for th
The Effects of Stereochemistry of the Bridging Atoms in o-Substituted Arylbenzoic Acids on Root Antigravitropism
Teitei, Tsutomu
, p. 1461 - 1466 (2007/10/02)
Compounds in which an aryl or heteroaryl ring is linked to the ortho position of a benzoic acid moiety by a bridging group of up to four atoms are shown to inhibit the gravitropic response of cress seedling roots between 1E-5 and 1E-8 M.No significant difference in inhibitory activity is observed between compounds containing up to four saturated or two partially unsaturated bridging atoms, although analogues containing three or four partially unsaturated bridging atoms are one to two orders of magnitude more active.Compounds in which the aryl nuclei are fused together are shown to be inactive at the highest concentration tested.The results have been interpreted in terms of the aryl groups in the molecule interacting with a hypothetical receptor site, with the bridging atoms acting as a more or less flexible coupling to facilitate such interaction.
