855245-86-2Relevant academic research and scientific papers
The N-Aryl aminocarbonyl ortho-substituent effect in Cu-catalyzed aryl amination and its application in the synthesis of 5-substituted 11-Oxo-dibenzodiazepines
Diao, Xiaoqiong,Xu, Lanting,Zhu, Wei,Jiang, Yongwen,Wang, Haoyang,Guo, Yinlong,Ma, Dawei
supporting information; experimental part, p. 6422 - 6425 (2012/02/03)
Double amination of ortho-substituted aryl bromides proceeded under mild conditions to afford 5-substituted 11-oxo-dibenzodiazepines, which revealed that there is a strong ortho-substituent effect caused by N-aryl aminocarbonyl groups during copper-cataly
Synthesis of 1,4-benzodiazepine-2,5-dione derivatives
Ho, Tong-Ing,Chen, Wen-Shiong,Hsu, Chi-Wei,Tsai, Yeun-Min,Fang, Jim-Min
, p. 1501 - 1506 (2007/10/03)
A synthesis of a series of 1,4-benzodiazepine-2,5-dione derivatives with a carboxy group at the 3-position is realized in good yields by using methyl malonylchloride as a key reagent and intramolecular nucleophilic substitution as ring closure reaction.
