85547-56-4 Usage
Uses
Used in Pharmaceutical Industry:
4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate is used as an anti-malarial medication for the treatment and prevention of malaria. Its anti-malarial properties are attributed to the 7-chloroquinoline moiety, which is a derivative of the well-known antimalarial drug, quinine.
Used in Antitumor Applications:
4,4'-(1,3-Propanediyldi-4,1-piperazinediyl)bis(7-chloroquinoline) phosphate has shown potential as an antitumor agent due to its ability to intercalate DNA and prevent its replication. This property makes it a promising candidate for further research and development in the field of oncology. However, more studies are needed to fully understand its therapeutic applications and optimize its use in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 85547-56-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,5,4 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 85547-56:
(7*8)+(6*5)+(5*5)+(4*4)+(3*7)+(2*5)+(1*6)=164
164 % 10 = 4
So 85547-56-4 is a valid CAS Registry Number.
InChI:InChI=1/C29H32Cl2N6.H3O4P/c30-22-2-4-24-26(20-22)32-8-6-28(24)36-16-12-34(13-17-36)10-1-11-35-14-18-37(19-15-35)29-7-9-33-27-21-23(31)3-5-25(27)29;1-5(2,3)4/h2-9,20-21H,1,10-19H2;(H3,1,2,3,4)
85547-56-4Relevant academic research and scientific papers
AN IMPROVED PROCESS FOR THE PREPARATION OF PIPERAQUINE
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Page/Page column 11-12, (2011/09/14)
The present invention relates to an improved process for the preparation of 7-chloro- 4-piperazin-1-yl-quinoline of formula (I), a key intermediate for the synthesis of Piperaquine or its pharmaceutically acceptable salts.
