85557-94-4Relevant academic research and scientific papers
Discovery of Diphenoxy Derivatives with Flexible Linkers as Ligands for β-Amyloid Plaques
Jia, Jianhua,Zhang, Longfei,Song, Jia,Dai, Jiapei,Cui, Mengchao
, p. 4089 - 4100 (2020/12/13)
The highly rigid and planar scaffolds with π-conjugated systems have been widely considered to be indispensable for β-amyloid (Aβ) binding ligands. In this study, a library of diphenoxy compounds with different types of more flexible linkers as Aβ ligands were synthesized and evaluated. Most of them displayed good affinity (Ki1-42aggregates, and some ligands even showed values of Kiless than 10 nM. Structure-activity relationship analysis revealed that modification on the linkers or substituents tolerated great flexibility, which challenged the long-held belief that rigid and planar structures are exclusively favored for Aβ binding. Three ligands were labeled by iodine-125, and they exhibited good properties in vitro and in vivo, which further supported that this flexible scaffold was potential and promising for the development of Aβ imaging agents.
Solid-Solid Phase Transitions in [ trans-Pt(PMe3)2(C=CC6H4R)2]-Containing Materials (R = O(CH2)nH; N = 6, 9, 12, and 15)
Marineau Plante, Gabriel,Fortin, Daniel,Soldera, Armand,Harvey, Pierre D.
supporting information, p. 2544 - 2552 (2018/08/21)
The title complexes were prepared in Hagihara conditions and were investigated by single crystal X-ray crystallography (n = 6, [Pt]C6; n = 12, [Pt]C12), X-ray powder diffraction (powder XRD), differential scanning calorimetry (DSC),
Synthesis and photovoltaic characterization of triarylamine-substituted quinoxaline push–pull dyes to improve the performance of dye-sensitized solar cells
Demirak, Kadir,Can, Mustafa,?zsoy, Cihan,Yi?it, Mesude Zeliha,Gültekin, Burak,Demi?, ?erafettin,Zafer, Ceylan
, p. 309 - 322 (2017/07/05)
Novel unsymmetrical organic sensitizers having donor, π-spacer, and anchoring groups were designed and synthesized for dye-sensitized solar cell (DSSC) application. The dyes 3-{4-[7-(4-{bis[4-(hexyl)phenyl]amino} phenyl)-11,12-dibutoxy-1,4,5,8-tetrahydrod
Structure-Directed Functional Properties of Phenothiazine Brominated Dyes: Morphology and Photophysical and Electrochemical Properties
Bejan, Andrei,Shova, Sergiu,Damaceanu, Mariana-Dana,Simionescu, Bogdan C.,Marin, Luminita
, p. 3716 - 3730 (2016/07/19)
A series of nine dyes based on electron-donating phenothiazine core functionalized with various carbonyl containing electron-withdrawing moieties as primary end group and with or without bromine as a second heavy end group were designed and synthesized to generate variable supramolecular architectures with distinct thermotropic, photophysical, and electrochemical properties. The supramolecular architecture of the obtained dyes was studied in detail by single crystal X-ray diffraction and polarized light microscopy, while optoelectronic properties were investigated by UV-vis and photoluminescence spectroscopy and cyclic voltammetry measurements. The phenothiazine dyes emit light from UV to orange domain, depending on the electron-withdrawing substituent, with great quantum yield reaching up to 71% and high color purity. The introduction of the bromine as a second substituent produced a nearly 2-fold increase of the quantum yield, compared with their counterparts. It was settled that this major benefit of the bromine on the improvement of the quantum yield happened because by its presence some molecular orbital interactions were generated. An interesting and challenging achievement was evidenced in the case of the direct connection of the formyl group to the phenothiazine ring when an unexpected planarization of the dye, unknown up to now in the literature, with drastic consequences on the photophysical and electrochemical behavior was attained. It was concluded that there is a close relationship between the nature of the building blocks of the phenothiazine dyes and their ability to promote favorable properties for different optoelectronic applications.
The effect of additional electron donating group on the photophysics and photovoltaic performance of two new metal free D-π-A sensitizers
Margalias, An.,Seintis,Yigit,Can,Sygkridou,Giannetas,Fakis,Stathatos
, p. 316 - 327 (2015/06/25)
The synthesis, photophysical, electrochemical and photovoltaic properties of two D-π-A organic sensitizers, having triphenylamine as electron donor (with or without additional electron donating hexyloxy group), carboxylic acid as electron acceptor and ben
The effect of different alkyl chains on the photovoltaic performance of D-π-A porphyrin-sensitized solar cells
Chen, Jiangzhao,Ko, Songguk,Liu, Linfeng,Sheng, Yusong,Han, Hongwei,Li, Xiong
, p. 3736 - 3746 (2015/05/20)
In this study, a series of novel D-π-A porphyrin sensitizers with different alkyl chains were designed and synthesized for dye-sensitized solar cells. The effects of different alkyl chains (methyl, methoxyl and hexyloxy groups) on the photophysical, electrochemical and photovoltaic performance were investigated systematically. The results indicate that the molar extinction coefficients of three dyes normally increase as the alkyl chain length increases. Furthermore, it is also found that the incident photo-to-current conversion efficiencies (IPCEs), short circuit current (Jsc) and open circuit voltage (Voc) of the dye-sensitized solar cells (DSSCs) based on WH-C1, YD20 and WH-C2 increase with the elongation of alkyl chains in the order of WH-C1 sc of 13.10 mA cm-2, a Voc of 831.10 mV, and a fill factor (FF) of 0.70.
A new sensitizer containing dihexyloxy-substituted triphenylamine as donor and a binary conjugated spacer for dye-sensitized solar cells
Damaceanu, Mariana-Dana,Mihaila, Mihai,Constantin, Catalin-Paul,Chisca, Stefan,Serban, Bogdan-Catalin,Diaconu, Cristian,Buiu, Octavian,Pavelescu, Emil Mihai,Kusko, Mihaela
, p. 53687 - 53699 (2015/06/30)
The synthesis and application to dye-sensitized solar cells (DSSC) of a new dihexyloxy-substituted triphenylamine-based organic dye is reported. The dye design, based on the push-pull concept, consists of dihexyloxy-substituted triphenylamine as an electr
Fluoranthene derivatives as blue fluorescent materials for non-doped organic light-emitting diodes
Kumar, Shiv,Kumar, Deepak,Patil, Yogesh,Patil, Satish
supporting information, p. 193 - 200 (2015/12/30)
In this study, we report synthesis of symmetrically and non-symmetrically functionalized fluoranthene-based blue fluorescent molecular materials for non-doped electroluminescent devices. The solid state structure of these fluorophores has been established
Copper-catalyzed reduction of alkyl triflates and iodides: An efficient method for the deoxygenation of primary and secondary alcohols
Dang, Hester,Cox, Nick,Lalic, Gojko
, p. 752 - 756 (2014/01/23)
We describe an effective method for catalytic reduction of 1°alkyl sulfonates, and 1°and 2°iodides in the presence of a wide range of functional groups. This Cu-catalyzed reaction provides a means for the effective deoxygenation of alcohols, as demonstrated by the highly selective reduction of 1°alcohols using a triflation/reduction sequence. A preliminary study of the reaction mechanism suggests that the reduction does not involve free-radical intermediates. Primarily reduced: The copper-catalyzed reduction of 1°alkyl sulfonates, and 1°and 2°iodides, which is effective in the presence of a wide range of functional groups, provides a means for the effective deoxygenation of alcohols. A preliminary study of the reaction mechanism suggests that the reduction does not involve free-radical intermediates. Copyright
NHC-copper hydrides as chemoselective reducing agents: Catalytic reduction of alkynes, alkyl triflates, and alkyl halides
Cox, Nick,Dang, Hester,Whittaker, Aaron M.,Lalic, Gojko
, p. 4219 - 4231 (2014/06/09)
The NHC-copper-catalyzed Z-selective semi-reduction of terminal and internal alkynes, as well as the NHC-copper-catalyzed reduction of primary alkyl triflates and primary and secondary alkyl iodides and bromides are described. The high chemoselectivity demonstrated in these examples illustrates the mild nature of copper hydride complexes as reducing agents, which have applications in synthetic chemistry beyond their traditional role in the reduction of activated alkenes and carbonyl compounds.
