85573-09-7Relevant articles and documents
Synthesis and evaluation of 2-aryl-1H-benzo[d]imidazole derivatives as potential microtubule targeting agents
Lee, Jung-Seop,Nimse, Satish Balasaheb,Shinde, Pramod B.,Song, In-ho,Song, Keum-soo,Warkad, Shrikant Dashrath,Yeom, Gyu Seong
, (2022/01/20)
Microtubule targeting agents (MTAs) are the potential drug candidates for anticancer drug discovery. Disrupting the microtubule formation or inhibiting the de-polymerization process by a synthetic molecule can lead to an excellent anticancer drug candidat
Ni nanoparticles: Mild and efficient catalyst for the chemoselective synthesis of 2-arylbenzimidazoles, 2-arylbenzothiazoles, and azomethines
Khurana, Jitender M.,Sneha,Vij, Kanika
experimental part, p. 2606 - 2616 (2012/08/08)
(Chemical Equation Presented) A new and efficient method has been developed for the synthesis of biologically significant 2-arylbenzimidazoles, 2-arylbenzothiazoles, and azomethines using recyclable and inexpensive polyvinyl pyrrolidone (PVP)-stabilized Ni nanoparticles in ethylene glycol at room temperature in excellent yields. Copyright Taylor & Francis Group, LLC.
Synthesis and antibacterial activities of some schiff bases
Ibrahim, Mohamed N.,Sharif, Salaheddin A. I.,El-Tajory, Ahmad N.,Elamari, Asma A.
experimental part, p. 212 - 216 (2012/02/04)
Schiff bases p-hydroxybenzylidene-2-carboxyaniline, p-nitrobenzylidene-2- carboxyaniline, p-(N, N-dimethyl)aminobenzylidene-2-carboxyaniline, N-(4-hydroxybezylidene)-benzene-1,2-diamine, N-(4-nitrobezylidene)benzene-1,2- diamine,N-(4-(N, N-dimethylaminobezylidene)benzene-1,2-diamine, N-(4-(N,Ndimethylamino) benzylidene)naphthalen-1-amine,N-(4-nitrobenzylidene) naphthalen-1-amine,N-(4-chlorobenzylidene)naphthalen-1-amine,sodium-4-(4-(N, N-dimethyl amino)benzylideneamino)naphthalene-1-sulfonate,sodium -4-(4-nitrobenzylideneamino) naphthalene-1-sulfonate and sodium-4-(4- chlorobenzylideneamino) naphthalene-1-sulfonate obtained by condensation of aniline and naphthylamine derivatives with some aromatic aldehydes were characterized by physical and spectral methods. The biological activity of these products were as antibacterial agents against three species of human pathogenic bacteria such as Escherichia coli, Staphylococcus aureus and Klebsiella sp. Nearly 50% of these compounds showed reasonable activity against the bacterial species investigated and we found that the antibacterial activity is dependent on the molecular structure of the compounds.