85576-96-1Relevant academic research and scientific papers
Base-promoted Reactions of α-Halogeno-alkylanilides
Cavicchioni, Giorgio,Scrimin, Paolo,Veronese, Augusto C.,Balboni, Gianfranco,D'Angeli, Ferruccio
, p. 2969 - 2972 (2007/10/02)
Hydride-promoted reactions of 2-halogeno-alkylcarboxanilides afford heterocyclic and acyclic condensation products, some of the latter compounds arising upon hydrolysis and/or rearrangement of the former ones.Competitive formation of dioxopiperazines versus oxazolidinone derivatives or their transformation products depends mainly upon the nature (primary, secondary or tertiary) of the halide moiety.Concurrent dehydrohalogenation of 2-bromo-isobutyranilides leads to unsaturated condensation products.
