855780-31-3Relevant academic research and scientific papers
A new class of inhibitors for the metalloprotease neprilysin based on a central imidazole scaffold
Sahli, Stefan,Stump, Bernhard,Welti, Tobias,Schweizer, W. Bernd,Diederich, Francois,Blum-Kaelin, Denise,Aebi, Johannes D.,Boehm, Hans-Joachim
, p. 707 - 730 (2005)
Neprilysin (NEP; neutral endopeptidase EC 3.4.24.11) is a Zn II-dependent, membrane-bound endopeptidase. NEP is widely distributed in the organs, particularly in the kidneys and lungs, and it is involved in the metabolism of a number of smaller
