855952-71-5Relevant academic research and scientific papers
Inhibition of subgenomic hepatitis C virus RNA replication by acridone derivatives: Identification of an NS3 helicase inhibitor
Manfroni, Giuseppe,Paeshuyse, Jan,Massari, Serena,Zanoli, Samantha,Gatto, Barbara,Maga, Giovanni,Tabarrini, Oriana,Cecchetti, Violetta,Fravolini, Arnaldo,Neyts, Johan
experimental part, p. 3354 - 3365 (2010/03/31)
We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a pot
