855985-39-6Relevant academic research and scientific papers
Enantioselective one-pot three-component synthesis of propargylamines
Bisai, Alakesh,Singh, Vinod K.
, p. 2405 - 2408 (2006)
A copper(I) complex of i-Pr-pybox-diPh has been found to be an efficient catalyst for an enantioselective one-pot three-component synthesis of propargylamines from aldehydes, amines, and alkynes. The reaction has been applied to a wide variety of aromatic
Asymmetric addition of alkynes to imines in water catalyzed with a recyclable Cu(I)-bis(oxazoline) and stearic acid system
Liu, Juntao,Liu, Bao,Jia, Xian,Li, Xingshu,Chan, Albert S.C.
, p. 396 - 399 (2007)
Stearic acid and its zinc salt were used as additives in the enantioselective alkyne addition to imines catalyzed by copper(I)-bis(oxazoline) (box) in water. The reactions took place smoothly with good yields and high enantioselectivities (up to 97% ee).
Enantioselective addition of phenyl and alkyl acetylenes to imines catalyzed by chiral Cu(I) complexes
Benaglia, Maurizio,Negri, Diego,Dell'Anna, Gianmaria
, p. 8705 - 8708 (2004)
The stereoselective addition of phenyl acetylene and alkyl acetylenes to imines, catalyzed by chiral bis-imines-Cu(I) complexes was studied. A very simple experimental procedure allowed to obtain at room temperature optically active propargyl amines in ve
Very mild, enantioselective synthesis of propargylamines catalyzed by copper(I)-bisimine complexes
Colombo, Federica,Benaglia, Maurizio,Orlandi, Simonetta,Usuelli, Fabio,Celentano, Giuseppe
, p. 2064 - 2070 (2006)
The stereoselective addition of aryl- and alkylacetylene derivatives to imines was studied. The reaction is catalyzed by copper complexes of enantiomerically pure bisimines, readily prepared in very high yields from the commercially available binaphthyl d
The first solid-phase synthesis of bis(oxazolinyl)pyridine ligands
Weissberg, Avi,Halak, Baruch,Portnoy, Moshe
, p. 4556 - 4559 (2005)
Chiral Pybox (pyridine-2,6-bis(oxazoline)) ligands can be cleanly and efficiently prepared on polystyrene support via a five-step solid-phase synthetic sequence. Cu(I)-complexed polymer-bound Pybox was used as a catalyst in the first heterogeneously catal
Chiral diamine-copper(I) complexes as asymmetric catalysts in the enantioselective addition of phenylacetylene to imines
Orlandi, Simonetta,Colombo, Federica,Benaglia, Maurizio
, p. 1689 - 1692 (2005)
The stereoselective addition of phenyl acetylene to imines, catalysed by chiral bis-amine-Cu(I) complexes was studied. The chiral ligands are either commercially available or easily prepared in one or two steps. This very convenient and extremely simple e
Synthesis of Silver(I) and Gold(I) Complexes Containing Enantiopure Pybox Ligands. First Assays on the Silver(I)-Catalyzed Asymmetric Addition of Alkynes to Imines
Borrajo-Calleja, Gustavo M.,De Julián, Eire,Bayón, Esther,Díez, Josefina,Lastra, Elena,Merino, Isabel,Gamasa, M. Pilar
, p. 8794 - 8807 (2016)
Dinuclear complexes [Ag2(CF3SO3){(S,S)-iPr-pybox}2][CF3SO3] (1), [Ag2(R-pybox)2][X]2 [R-pybox = 2,6-bis[4-(S)-isopropyloxazolin-2-yl]pyridine (S,
Chiral Cu(II) complex catalyzed enantioselective addition of phenylacetylene to N-aryl arylimines
Liu, Bao,Huang, Ling,Liu, Juntao,Zhong, Yao,Li, Xingshu,Chan, Albert S.C.
, p. 2901 - 2904 (2007)
Chiral tridentate N-tosylated aminoimine ligands were used in the Cu(II)-catalyzed enantioselective addition of phenylacetylene to N-aryl arylimines, affording products up to 92% ee.
Combined Dynamic Kinetic Resolution and C?H Functionalization for Facile Synthesis of Non-Biaryl-Atropisomer-Type Axially Chiral Organosilanes
Li, Zhao,Wang, Xu,Cui, Yu-Ming,Ma, Jun-Han,Fang, Li-Lei,Han, Lu-Lu,Yang, Qin,Xu, Zheng,Xu, Li-Wen
supporting information, p. 4336 - 4340 (2021/02/16)
Although asymmetric C?H functionalization has been available for the synthesis of structurally diverse molecules, catalytic dynamic kinetic resolution (DKR) approaches to change racemic stereogenic axes remain synthetic challenges in this field. Here, a c
Utilization of CO2 as a C1 Building Block in a Tandem Asymmetric A3 Coupling-Carboxylative Cyclization Sequence to 2-Oxazolidinones
Gao, Xiao-Tong,Gan, Chen-Chen,Liu, Si-Yue,Zhou, Feng,Wu, Hai-Hong,Zhou, Jian
, p. 8588 - 8593 (2017/12/08)
We report a tandem asymmetric aldehyde-alkyne-amine (A3) coupling-carboxylative cyclization sequence for the highly enantioselective synthesis of chiral N-aryl 2-oxazolidinones. This is a rare example of a multicatalyst-promoted asymmetric tand
