856013-03-1Relevant academic research and scientific papers
ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS
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Paragraph 0851, (2017/03/14)
Compounds, methods of use, and processes for making inhibitors of complement Factor D are provided comprising Formula I, I" and I'" or a pharmaceutically acceptable salt or composition thereof. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduces the excessive activation of complement.
PHENETHANOLAMINE DERIVATIVES FOR TREATMENT OF RESPIRATORY DISEASES
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Page/Page column 41, (2010/02/12)
Compounds of formula (I): Wherein: R1 is-XSO2NR6R7; wherein X is -(CH2)p - or C2-6 alkenylene; p is an integer from 0 to 6; Ar2 is a mono or bicyclic heteroaryl or a b
