85603-33-4

Basic information

• Product Name: 3-(dimethylamino)-1,1-diphenyl-1-(prop-2-yn-1-yloxy)propan-2-one hydrochloride
• CAS NO: 85603-33-4
• Molecular Formula: C₂₀H₂₁NO₂*ClH
• Molecular Weight: 343.8472
• Mol File: 85603-33-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 436.2°C at 760 mmHg
• Flash Point: 217.6°C
• Vapor Pressure: 8.26E-08mmHg at 25°C
• CAS DataBase Reference: 3-(dimethylamino)-1,1-diphenyl-1-(prop-2-yn-1-yloxy)propan-2-one hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(dimethylamino)-1,1-diphenyl-1-(prop-2-yn-1-yloxy)propan-2-one hydrochloride(85603-33-4)
• EPA Substance Registry System: 3-(dimethylamino)-1,1-diphenyl-1-(prop-2-yn-1-yloxy)propan-2-one hydrochloride(85603-33-4)

Safety Data

• Hazardous Substances Data: 85603-33-4(Hazardous Substances Data)

Upstream product

• 85603-24-3 1,1-Diphenyl-1-prop-2-ynyloxy-propan-2-one 
• 33718-91-1 1,1-diphenyl-1-bromo-2-propanone 
• 124-40-3 dimethyl amine 

Relevant articles and documents

The synthesis of some 1,1-diphenyl-1-alkoxy-3-alkylamino-2-propanones''' of biological interest

The synthesis of 1,1-diphenyl-1-alkoxy-3-alkylamino-2-propanones is reported. For this synthesis the following series of reactions was utilized: 1-phenyl-1-propanone was brominated, the product reacted with benzene (Friedel-Crafts), the 1,1-diphenyl-3-propanone was brominated, then reacted with the appropriate alcohol, the alkoxy derivative was brominated and then reacted with the appropriate amine. The synthesized compounds were tested for analgesic activity. All test compounds showed weak analgesic action, the most active were 1,1-diphenyl-1-ethoxy-3-piperidino-2-propanone and 1,1-diphenyl-1-phenoxy-3-dimethylamino-2-propanone.