85604-63-3Relevant academic research and scientific papers
A Highly Efficient and Chemoselective Synthetic Protocol for Tetrahydropyranylation/Depyranylation of Alcohols and Phenols
Khan, Abu T.,Mondal, Ejabul,Borah, Ballav M.,Ghosh, Subrata
, p. 4113 - 4117 (2007/10/03)
Various alcohols and phenols can be converted efficiently to the corresponding tetrahydropyranyl (THP) ethers in good yields using catalytic amounts of bromodimethylsulfonium bromide (0.005-0.02 equivalent) at room temperature. On the other hand, various THP ethers can also be deprotected to the parent alcoholic or phenolic compounds in CH2Cl2/ MeOH (5:2) by employing 0.05 equivalent of the same catalyst. Some of the major advantages of this procedure are its mild conditions, that it is highly selective and efficient, high yielding, and cost-effective, that it needs no solvent and is compatible with the presence of other protecting groups. Furthermore, no brominations occur at a double or triple bond, at an allylic position or even at an aromatic ring. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
Syntheses d'aryltetrahydropyrannyl ethers
Cottet, Francoise,Cottier, Louis,Descotes, Gerard,Srivastava, Rajendra Mohan
, p. 1481 - 1486 (2007/10/02)
L'addition de methoxyphenols 1 sur le dihydropyranne en milieu acide donne des produits C- et/ou O-tetrahydropyrannyles 3 et 4 dont le pourcentage est fonction du nombre de substituants methoxy et de la force du catalyseur acide.Les aryl tetrahydropyranny
