856112-61-3Relevant academic research and scientific papers
A versatile synthesis of annulated carbazole analogs involving a domino reaction of bromomethylindoles with arenes/heteroarenes
Dhayalan, Vasudevan,Clement, J. Arul,Jagan, Radhakrishnan,Mohanakrishnan, Arasambattu K.
supporting information; experimental part, p. 531 - 546 (2009/09/06)
A ZnBr2-mediated arylation of aryl/heteroaryl methyl bromides with arenes at 80°C led to the formation of arylated products, which underwent subsequent 1,5-sigmatropic rearrangement followed by electrocyclization and aromatiza tion with loss of a diethylmalonate unit to afford the corresponding annulated products.
Synthesis of N-protected indolaldehydes using modified Hass procedure
Balamurugan, Ramalingam,Mohanakrishnan, Arasambattu K.
, p. 11078 - 11085 (2008/02/12)
A detailed study on oxidation of N-protected bromomethylindoles into the respective aldehydes was carried out. Using a modified Hass procedure, synthesis of aryl-/hetero-aryl aldehydes in particular indolaldehydes is achieved in reasonable yields.
Stille carbonylation of N-protected bromomethylindoles
Mohanakrishnan, Arasambattu K.,Ramesh, Neelamegam
, p. 4577 - 4579 (2007/10/03)
A variety of N-protected indolylmethylbromides are carbonylated using 5 mol % Pd(PPh3)2Cl2 under Stille conditions in the presence of an alcohol to afford the corresponding methyl/ethyl esters.
An efficient preparation of 1-phenylsulfonylindolyl methyl sulfoxides using KF/m-CPBA
Mohanakrishnan, Arasambattu K.,Ramesh, Neelamegam
, p. 4231 - 4233 (2007/10/03)
A variety of 1-phenylsulfonylindolylmethyl sulfides are selectively oxidized to the corresponding sulfoxides using a hitherto unexplored KF/m-CPBA system. A major advantage is the absence of over-oxidation.
A Versatile Construction of the 8H-Quinocarbazole Ring System as a Potential DNA Binder
Mohanakrishnan, Arasambattu K.,Srinivasan, Panayencheri C.
, p. 1939 - 1946 (2007/10/02)
A short synthesis of the quino- and quinocarbazoles is repoerted.The key step of the synthesis involves the preparation of suitable 2,3-divinylindoles by consecutive Wittig reactions.The thermal electrocyclic reaction of the divinylindole wi
