856167-33-4

Upstream product

• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 
• 68837-59-2 4-bromo-2-methylbenzoic acid 
• 21900-45-8 4-bromo-2-methylbenzoyl chloride 

Downstream Products

• 858209-29-7 N-benzenesulfonyl-N'-(4-bromo-2-methyl-benzoyl)-hydrazine 
• 942273-34-9 C₁₅H₁₁BrN₂O 
• 942273-36-1 C₁₅H₁₂BrN₃ 
• 856167-32-3 N'-(3-cyano-4-isopropyloxyphenylcarbonyl)-4-bromo-2-methylbenzhydrazide 
• 24106-06-7 4-bromo-2-methyl-benzaldehyde-(2,4-dinitro-phenylhydrazone) 
• 879407-22-4 2,2'-dimethyl-trans-stilbene-dicarbonitrile-(4.4') 
• 879407-83-7 2,2'-dimethyl-cis-stilbene-dicarbonitrile-(4.4') 
• 878654-40-1 2,3t-bis-(4-bromo-2-methyl-phenyl)-acrylic acid 
• 91445-82-8 4-bromo-2-methyl-trans-cinnamic acid 
• 90914-83-3 4-bromo-2-methyl-benzaldehyde-semicarbazone 
• 24078-12-4 4-bromo-2-methylbenzaldehyde 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of phenyloxadiazole derivatives as potential antifungal agents against phytopathogenic fungi

Abstract: A novel series of picarbutrazox-inspired oxadiazole hybrids was synthesized and the derivatives’ biological activity against phytopathogenic fungi was investigated. The molecules were designed by retaining the active fragment of tetrazolyl phenyloxime ether of lead compound picarbutrazox, while introducing the potentially active oxadiazole-derived fragment. Bioassay results revealed that some of the title compounds showed potent in vivo antifungal activities to control cucumber downy mildew. Therefore, this novel oxadiazole phenyloxadiazole derivative can be used as a potential antifungal agent to control cucumber downy mildew and other phytopathogenic fungi for crop protection. Graphic abstract: [Figure not available: see fulltext.].

Preparation of novel anthranilic acids as antibacterial agents. Extensive evaluation of alternative amide bioisosteres connecting the A- and the B-rings

In the past few years, a significant effort has been devoted by Pharmacia toward the discovery of novel antibiotics. We have recently described the identification of an anthranilic acid lead 1 and the optimization resulting in the advanced lead 2. In this report, we describe the preparation of several selected amide bioisosteres connecting the A- and the B-rings. The E-alkene provided a rigid analog with equal potency to the corresponding amide. This indicates that the amide is not a recognition element rather acts as an appropriate spatial linker of the two important aryl A and B rings. The work here clearly demonstrates that the amide linker can be replaced with several functionalities without significant deterioration in the MIC activity.