85620-84-4

Usage

Uses

Used in Fragrance and Flavoring Industry:
(S)-3,6-DIHYDRO-2H-PYRAN-3-OL is used as a key ingredient in the fragrance and flavoring industry for its distinctive floral scent and sweet taste, which are highly desirable in creating various perfumes, colognes, and flavor additives for the food and beverage sector.
Used in Aromatherapy and Traditional Medicine:
In the field of aromatherapy and traditional medicine, (S)-3,6-DIHYDRO-2H-PYRAN-3-OL is utilized as a natural remedy for its anti-inflammatory, anxiolytic, and sedative effects, helping to alleviate stress, anxiety, and promote relaxation.
Used in Insect Control:
(S)-3,6-DIHYDRO-2H-PYRAN-3-OL is employed as a natural insecticide, particularly effective against mosquitoes and fruit flies, offering an eco-friendly alternative to chemical pesticides for pest control.
Used in Pharmaceutical Research:
(S)-3,6-DIHYDRO-2H-PYRAN-3-OL is also used in pharmaceutical research for its potential anti-cancer properties, with ongoing studies exploring its effectiveness in combating various types of cancer.

InChI:InChI=1/C5H8O2/c6-5-2-1-3-7-4-5/h1-2,5-6H,3-4H2/t5-/m0/s1

Upstream product

• 85620-83-3 (3aR,7R,7aS)-2-Ethoxy-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol 
• 32742-34-0 1,5-Anhydro-D-arabinitol 
• 3152-43-0 3,4-di-O-acetyl-D-xylal 
• 3152-43-0 3,4-di-O-acetyl-D-arabinal 
• 50-69-1 D-Arabinose 
• 528869-25-2 (3S,4R,5R)-2-Bromo-tetrahydro-pyran-3,4,5-triol 
• 3068-29-9 2,3,4-tri-O-acetyl-β-D-arabinosyl bromide 
• 62445-02-7 2,3,4-tri-O-acetyl-1,5-anhydro-D-arabinitol 

Downstream Products

• 85620-85-5 3R-3,6-dihydro-2H-pyranyl-N,N-dimethylacetamide 
• 85620-92-4 2-((3S,4S)-4-Hydroxy-3,4-dihydro-2H-pyran-3-yl)-N-phenyl-acetamide 
• 85620-93-5 N,N-Dimethyl-2-((2S,5R)-5-phenylcarbamoylmethyl-5,6-dihydro-2H-pyran-2-yl)-acetamide 
• 87614-56-0 5S-iodo-1S,6S-3,7-dioxabicyclo<4,3,0>nonan-8-one 
• 87614-58-2 (3S,4S)-3-(2-Hydroxy-ethyl)-3,4-dihydro-2H-pyran-4-ol 
• 87614-59-3 (3S,4S)-3-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,4-dihydro-2H-pyran-4-ol 
• 75452-45-8 C₂₅H₄₀O₆ 
• 87614-60-6 2-{(2S,5R)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-5,6-dihydro-2H-pyran-2-yl}-N,N-dimethyl-acetamide 
• 87641-25-6 C₃₆H₅₀O₆Si 
• 87614-61-7 C₄₀H₄₄O₇Si 
• 87678-98-6 1-{(2S,5R)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-5,6-dihydro-2H-pyran-2-yl}-propan-2-one 
• 87678-99-7 1-{(2S,3R,4R,5S)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,4-dihydroxy-tetrahydro-pyran-2-yl}-propan-2-one 
• 71980-98-8 pseudomonic acid C 
• 12650-69-0 mupirocin 

Relevant academic research and scientific papers

CHOLINE METABOLISM INHIBITORS

The present disclosure relates to compounds, compositions and methods for inhibiting choline metabolism, e.g., conversion of choline to trimethylamine. Disclosed herein are compounds, compositions, and methods for inhibiting choline metabolism, e.g., conversion of choline to TMA. Also disclosed herein are compounds, methods and compositions for inhibiting choline metabolism by gut microbiota resulting in reduction in the formation of trimethylamine (TMA) and trimethylamine N-oxide (TMAO).

COMPOUNDS AND COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO NTRK

This invention relates to inhibitors of NTRK that are active against wild-type NTRK and its resistant mutants.

Synthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitors

The development of 1,3,4,4a,5,10a-hexahydropyrano[3,4-b]chromene analogs as BACE1 inhibitors is described. Introduction of the spirocyclic pyranochromene scaffold yielded several advantages over previous generation cores, including increased potency, reduced efflux, and reduced CYP2D6 inhibition. Compound 13 (BACE1 IC50 = 110 nM) demonstrated a reduction in CSF Aβ in wild type rats after a single dose.

Novel olefin-phosphorus hybrid and diene ligands derived from carbohydrates

Starting from readily available monosaccharides d-glucose and d-arabinose, a family of novel chiral diene and olefin-phosphinite hybrid ligands has been designed. These ligands were prepared by attaching phosphinite or allylic donor sites onto unsaturated carbohydrate scaffolds. In rhodium(I)-catalysed conjugate addition of boronic acids to enones, the olefin-phosphinite hybrids gave products in up to 99% ee and above, whereas the dienes only led to modest enantioselectivity. However, by shifting the allylic donor sites from position 4 of the pyranose to the anomeric centre, an unexpected reversal of the stereoinduction process was observed. Georg Thieme Verlag Stuttgart New York.

ENANTIOSPECIFIC TOTAL SYNTHESIS OF PSEUDOMONIC ACIDS FROM ARABINOSE

The enantiospecific synthesis of pseudomonic acids from arabinose is described.

ENANTIOSPECIFIC SYNTHESES OF INTERMEDIATES IN THE TOTAL SYNTHESIS OF PSEUDOMONIC ACIDS

Enantiospecific syntheses of 1S,6S-3,7-dioxabicyclonon-4-en-8-one (1) and of the enantiomer (2) from D- and L-arabinose respectively have been achieved by two different routes.The conversion of (1) to 6S-(3R-acetanilido)-3,6-dihydro-2H-pyranyl-N,N-dimethylacetamide (3), a key intermediate in the synthesis of pseudomonic acids, is described.