85643-93-2Relevant academic research and scientific papers
STRUCTURE OF ISOSILEROLIDE, RELATIVE AND ABSOLUTE CONFIGURATION OF SILEROLIDE AND LASOLIDE - SESQUITERPENIC LACTONES OF NEW STEREOISOMERIC TYPE OF EUDESMANOLIDES
Holub, Miroslav,Budesinsky, Milos,Smitalova, Zdenka,Saman, David,Rychlewska, Urszula
, p. 903 - 929 (2007/10/02)
On the basis of spectroscopic, particularly 1H NMR data, isosilerolide was assigned structure I, including the absolute configuration.The structure was confirmed by X-ray diffraction.Isosilerolide represents a new stereoisomeric type of natural eudesmanolides, characterized as 5βH,6αH,7αH,10αCH3-eudesman-6,12-olide.As shown by the chemical correlation of isosilerolide (I) with silerolide (III) and lasolide (X), the latter two natural lactones belong to this stereoisomeric group of eudesmanolides.Analysis of models and 1H NMR data shows that structures of some eudesman-6,12-olides, published by other authors, should be corrected.
