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(1S,2R,3R)-1-t-butoxycarbonylamino-2-methyl-3-phenyl-cyclopropanecarboxylic acid t-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

856432-51-4

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856432-51-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 856432-51-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,6,4,3 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 856432-51:
(8*8)+(7*5)+(6*6)+(5*4)+(4*3)+(3*2)+(2*5)+(1*1)=184
184 % 10 = 4
So 856432-51-4 is a valid CAS Registry Number.

856432-51-4Relevant academic research and scientific papers

Synthesis and SAR of 2-phenyl-1-sulfonylaminocyclopropane carboxylates as ADAMTS-5 (Aggrecanase-2) inhibitors

Shiozaki, Makoto,Imai, Hiroto,Maeda, Katsuya,Miura, Tomoya,Yasue, Katsutaka,Suma, Akira,Yokota, Masahiro,Ogoshi, Yosuke,Haas, Julia,Fryer, Andrew M.,Laird, Ellen R.,Littmann, Nicole M.,Andrews, Steven W.,Josey, John A.,Mimura, Takayuki,Shinozaki, Yuichi,Yoshiuchi, Hiromi,Inaba, Takashi

scheme or table, p. 6213 - 6217 (2010/06/19)

A series of 1-sulfonylaminocyclopropanecarboxylates was synthesized as ADAMTS-5 (Aggrecanase-2) inhibitors. After an intensive investigation of the central cyclopropane core including its absolute stereochemistry and substituents, we found compound 22 wit

CYCLOPROPANE COMPOUNDS AND PHARMACEUTICAL USE THEREOF

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Page/Page column 181, (2008/06/13)

The present invention provides a compound having aggrecanase inhibitory activity and MMP-13 inhibitory activity, and useful as a therapeutic agent for osteoarthritis, rheumatoid arthritis and the like, more specifically, a cyclopropane compound of formula

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