85655-96-5

Upstream product

• 85655-99-8 hex-3-yne-1,6-diyl diacetate 
• 501-65-5 diphenyl acetylene 
• 591-50-4 iodobenzene 
• 56703-55-0 but-3-yn-1-yl acetate 

Downstream Products

• 85655-99-8 hex-3-yne-1,6-diyl diacetate 
• 501-65-5 diphenyl acetylene 

Relevant academic research and scientific papers

Direct Conversion of Internal Alkynes into α-Iodoenones: One-Step Collaborative Iodination and Oxidation

The reaction of an internal alkyne with 2,6-dichloropyridine N-oxide, a nucleophilic oxidant, and electrophilic N-iodosuccinimide (NIS) simultaneously enables the direct access to versatile α-iodoenones. Electronically biased internal alkynes undergo the one-step transformation with excellent regioselectivities and with practical Z/E ratios. In comparison to the related oxidative gold catalysis using pyridine N-oxides, this reaction employs NIS as the stoichiometric ynophile instead of the soft acidic noble metal catalyst and affords products featuring an additional versatile C-I bond. Similar strategies for replacing ynophilic cationic gold(I) complexes in oxidative gold catalysis with likewise ynophilic stoichiometric electrophiles would enable the development of new synthetic methods.

HOMOGENEOUS METATHESIS OF FUNCTIONALISED ACETYLENES

The first examples of functionalised acetylenes metathesis are described: (1) using molybdenum carbonyl-phenol complexes gave the expected tolane (2) and disubstituted acetylene (3).