56703-55-0

Basic information

• Product Name: 3-BUTYNYL-1-ACETATE
• Synonyms: 3-BUTYNYL-1-ACETATE;3-BUTINYL-1-ACETATE
• CAS NO: 56703-55-0
• Molecular Formula: C₆H₈O₂
• Molecular Weight: 112.13
• Product Categories: pharmacetical
• Mol File: 56703-55-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 141.7°C at 760 mmHg
• Flash Point: 39.4°C
• Appearance: /
• Density: 0.976g/cm³
• Vapor Pressure: 5.78mmHg at 25°C
• Refractive Index: 1.426
• CAS DataBase Reference: 3-BUTYNYL-1-ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BUTYNYL-1-ACETATE(56703-55-0)
• EPA Substance Registry System: 3-BUTYNYL-1-ACETATE(56703-55-0)

Safety Data

• Hazardous Substances Data: 56703-55-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H8O2/c1-3-4-5-8-6(2)7/h1H,4-5H2,2H3

Upstream product

• 108-24-7 acetic anhydride 
• 927-74-2 3-Butyn-1-ol 
• 75-05-8 acetonitrile 
• 627-10-1 2-iodoethyl acetate 
• 1066-54-2 trimethylsilylacetylene 
• 75-36-5 acetyl chloride 

Downstream Products

• 1576-84-7 1-acetoxy-3-butene 
• 258331-45-2 Acetic acid (E)-8-benzyloxy-3-methylene-oct-4-enyl ester 
• 6564-95-0 4-oxobutyl acetate 
• 10150-87-5 1-acetoxybutan-3-one 

Relevant articles and documents

IrIII-Catalyzed direct syntheses of amides and esters using nitriles as acid equivalents: A photochemical pathway

An unprecedented IrIII[df(CF3)ppy]2(dtbbpy)PF6-catalyzed simple photochemical process for direct addition of amines and alcohols to the relatively less reactive nitrile triple bond is described herein. Various amides and esters are synthesized as the reaction products, with nitriles being the acid equivalents. A mini-library of different types of amides and esters is made using this mild and efficient process, which uses only 1 mol% of photocatalyst under visible light irradiation (λ = 445 nm). The reaction strategy is also efficient for gram-scale synthesis.

Conjugated dialkynyl-1-ol compounds, and preparation method and application thereof

The invention belongs to the technical field of pharmacochemistry, and particularly relates to conjugated dialkynyl-1-ol compounds, and a preparation method and application thereof. The preparation method of conjugated dialkynyl-1-ol compounds comprises the following steps: carrying out Cardiot-Chodkiewicz coupling reaction on (Z)-(5-bromoamyl-2-ene-4-alkynyloxy)tert-butyl diphenyl silane and alkynyl butanol to generate (Z)-9-tert-butyl-diphenylsiloxynonyl-7-ene-3,5-dialkynyl-1-ol, and carrying out alkylation reaction on the (Z)-9-tert-butyl-diphenylsiloxynonyl-7-ene-3,5-dialkynyl-1-ol to generate (Z)-9-tert-butyl-diphenylsiloxynonyl-7-ene-3,5-dialkynyl-1-alkyl ether, wherein R1=CH3(CH2)n (n=0-6), or CH2O(CH2)nCH3 (n=0-6); and carrying out deprotection on the (Z)-9-tert-butyl-diphenylsiloxynonyl-7-ene-3,5-dialkynyl-1-alkyl ether to obtain (Z)-nonyl-2-ene-4,6-dialkynyl-9-ol-1-alkyl ether, wherein R1=CH3(CH2)n (n=0-6), or CH2O(CH2)nCH3 (n=0-6).

Discovery of an 8-aza-5-thiaProstaglandin E1 analog as a highly selective EP4 receptor agonist

For the purpose of discovering an orally available EP4 subtype-selective agonist, a series of 8-aza prostaglandin E1 (PGE1) analogs were synthesized and evaluated for their affinity for PGE2 receptor subtypes. Additionally