85681-42-1

Basic information

• Product Name: 2-Ethyl-benzoic acid [1-amino-1-(3-methoxy-phenyl)-meth-(Z)-ylidene]-hydrazide
• Synonyms: 2-Ethyl-benzoic acid [1-amino-1-(3-methoxy-phenyl)-meth-(Z)-ylidene]-hydrazide
• CAS NO: 85681-42-1
• Molecular Weight: 297.357
• Mol File: 85681-42-1.mol

Chemical Properties

• CAS DataBase Reference: 2-Ethyl-benzoic acid [1-amino-1-(3-methoxy-phenyl)-meth-(Z)-ylidene]-hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethyl-benzoic acid [1-amino-1-(3-methoxy-phenyl)-meth-(Z)-ylidene]-hydrazide(85681-42-1)
• EPA Substance Registry System: 2-Ethyl-benzoic acid [1-amino-1-(3-methoxy-phenyl)-meth-(Z)-ylidene]-hydrazide(85681-42-1)

Safety Data

• Hazardous Substances Data: 85681-42-1(Hazardous Substances Data)

Upstream product

• 55308-52-6 ethyl 3-methoxybenzimidate 
• 59635-98-2 2-ethylbenzoic acid hydrazide 
• 76118-05-3 2-ethylbenzoyl chloride 
• 612-19-1 2-ethylbenzoic acid 

Downstream Products

• 69095-83-6 3-(o-ethylphenyl)-5-(m-methoxyphenyl)-1H-1,2,4-triazole 

Relevant articles and documents

A New Class of Nonhormonal Pregnancy-Terminating Agents. Synthesis and Contragestational Activity of 3,5-Diaryl-s-triazoles

A series of 3,5-diaryl-s-triazoles were synthesized and evaluated as postimplantation contragestational agents.The introduction of various substituents (e.g., an o-alkyl chain on one phenyl and a m-alkoxy group on the other) was found to increase the potency.Several compounds with very high pregnancy-terminating activity in both hamsters and rats were obtained.One of these, 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-s-triazole, DL 111 (36), was selected for detailed evaluation in various animal species.A synthetic scheme for the preparation of these compounds and preliminary structure-activity relationships are presented.