856839-85-5Relevant academic research and scientific papers
The highly stereoselective formation of pipecolic acid N-oxide and related derivatives
O'Neil, Ian A.,Potter, Andrew J.
, p. 5731 - 5734 (2007/10/03)
N-Alkylated derivatives of pipecolic acid are shown to undergo highly stereoselective oxidation to give stable tertiary amine N-oxides. The ester derivatives show a high degree of stability compared to their proline analogues.
ENANTIOMERIC QUANTIFICATIONS OF AMINO ACIDS THROUGH THEIR Nα-ACYL AMIDES BY GAS CHROMATOGRAPHY.
Hosten, N.,Anteunis, M. J. O.
, p. 45 - 47 (2007/10/02)
Apparent separation of 1.1 or higher on Chiralsil Val III can be obtained for Nα-acyl N-alkyl aminoacid amides allowing the use of short capillary gas chromatographic columns.A clean derivatization protocol without racemization is described, proceding through the NCA derivatives that are prepared from "in situ" silylated amino acids with trimethylsilyl cyanide.
