856893-61-3Relevant academic research and scientific papers
MACROCYCLIC SULFONYLUREA DERIVATIVES USEFUL AS NLRP3 INHIBITORS
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Page/Page column 156-157, (2021/02/26)
The present invention relates to macrocyclic compounds, such as macrocyclic sulfonyl ureas. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions and to the use of such compounds in the treatment and
Total synthesis of nigellicine and nigeglanine hydrobromide
Elliott, Eric L.,Bushell, Simon M.,Cavero, Marta,Tolan, Brian,Kelly, T. Ross
, p. 2449 - 2451 (2007/10/03)
(Chemical Equation Presented) The first syntheses of the pyridazinoindazolium alkaloids nigellicine and nigeglanine hydrobromide via a common intermediate are described. Ortho-lithiation/acylation and the direct amination of an isatin ring system are the
