85690-31-9Relevant academic research and scientific papers
A simple and efficient procedure for the preparation of benzal chlorides and benzal bromides
Léonel, Eric,Paugam, Jean-Paul,Heintz, Monique,Nédélec, Jean-Yves
, p. 4015 - 4024 (1999)
Benzal chlorides and benzal bromides were conveniently synthesized by reaction of aryl aldehydes with a Vilsmeier type reagent formed in situ by reduction of CCl4 or CBr4 in dimethylformamide (DMF) as solvent.
Formamide Catalysis Facilitates the Transformation of Aldehydes into Geminal Dichlorides
Huy, Peter Helmut
supporting information, p. 2474 - 2483 (2019/06/08)
Herein, a novel method for the transformation of aldehydes into geminal dichlorides based on phthaloyl chloride as reagent and N -formylpyrrolidine as Lewis base catalyst is disclosed. Given the mild reaction conditions, the current protocol is distinguished by high levels of functional group compatibility and scalability and is operationally simple. The in situ formation of a Vilsmeier Haack reagent type intermediate is likely to be essential for this organocatalytic nucleophilic substitution reaction.
SYNTHESIS OF meta-SUBSTITUTED 9-PHENYLXANTHENES
Hinds, John L.,Rajadhyaksha, Shirish N.,Wander, Joseph D.
, p. 481 - 487 (2007/10/02)
Construction of the dibenzopyran ring of 9-(3-methoxyphenyl)xanthene (2) by an aluminum chloride-catalyzed, geminal dialkylation reaction between 3-methoxybenzal chloride and phenyl ether was accomplished, but in poor yield; however, a satisfactory prepar
