856900-26-0

Usage

Uses

Used in Pharmaceutical Industry:
N-Boc-3-Cyano-8-azabicyclo[3.2.1]octane is used as a building block for the synthesis of various biologically active molecules and pharmaceuticals. Its presence in the compound allows for the creation of a wide range of therapeutic agents.
Used in Medicinal Chemistry:
N-Boc-3-Cyano-8-azabicyclo[3.2.1]octane is used as a key intermediate in the development of new drugs. Its unique structure and synthetic versatility contribute to the design and synthesis of potential pharmaceuticals.
Used in Organic Synthesis:
N-Boc-3-Cyano-8-azabicyclo[3.2.1]octane is used as a versatile intermediate in organic synthesis, enabling the creation of a variety of chemical compounds for research and industrial applications.
Overall, N-Boc-3-Cyano-8-azabicyclo[3.2.1]octane is an important compound in the fields of medicinal chemistry, drug development, and organic synthesis, with potential applications in the creation of new pharmaceuticals and other chemical products.

Upstream product

• 10564-55-3 1-isocyanatomethanesulfonyl-4-methyl-benzene 
• 185099-67-6 Boc-tropinone 
• 24424-99-5 di-tert-butyl dicarbonate 
• 25602-68-0 3-oxo-8-azabicyclo[3.2.1]octane hydrochloride 
• 478837-18-2 3-exo-hydroxy-8-azabicyclo[3.2.1]octane-8carboxylic acid tert-butyl ester 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 

Downstream Products

• 856900-27-1 8-[1-(4-ethyl-phenyl)-methanoyl]-8-aza-bicyclo [3.2.1]octane-3-carboxylic acid ethyl ester 
• 1159826-74-0 8-(tert-butoxycarbonyl)-8-azabicyclo[3.2.1]octane-3-carboxylic acid 
• 799283-62-8 tert-butyl 3-(hydroxymethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 1159826-40-0 tert-butyl 3-(aminomethyl)-8-azabicyclo[3.2.1]octane-8-carboxylate 

Relevant academic research and scientific papers

3-aryl azabicyclo derivative as well as preparation and application thereof in nematode killing

The invention relates to preparation of a 3-aryl azabicyclo derivative and application of the derivative in nematode killing. Specifically, the invention discloses application of a compound with a structure as shown in a formula (I) or a composition, an optical isomer, a cis-trans-isomer and an agricultural pharmacologically acceptable salt of the compound in the field of nematode killing.

Compound and application thereof

The invention provides a novel compound. The novel compound has certain inhibitory activity for indoleamine 2,3-dioxygenase (IDO) which is oxido-reductase, and accordingly the novel compound can be used for treating diseases related to the indoleamine 2,3-dioxygenase and can be applied to cancer and immunity related diseases.

ANALOGUES OF 4H-PYRAZOLO[1,5-a] BENZIMIDAZOLE COMPOUND AS PARP INHIBITORS

Disclosed is a series of analogues of 4H-pyrazolo[1,5-α]benzimidazole compound as PARP inhibitors. In particular, disclosed in the invention is a compound as shown by formula (I) or a pharmaceutically acceptable salt thereof as a PARP inhibitor.

NITROGENOUS HETEROCYCLIC DERIVATIVE HAVING 2,6-DISUBSTITUTED STYRYL

The invention provides a novel nitrogen-containing heterocyclic derivative having 2,6-disubstituted styryl and a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the nitrogen-containing heterocyclic derivative and a pharmaceutically acceptable salt thereof, in particular, a pharmaceutical composition effective as a sodium channel inhibitor, having an excellent analgesic action especially on neuropathic pain with minimized side effects.

GLYCINE TRANSPORTER-1 INHIBIRORS

The invention provides a compound of formula (I) or a salt or solvate thereof: wherein R1, and R3 and R10, X and Ar are as defined in the specification, and uses of such compounds. The compounds inhibit GlyT1 transporters