478837-18-2

Basic information

• Product Name: tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
• Synonyms: 1-(METHYLSULFONYL)PIPERIDIN-4-AMINE HYDR;N-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane;2-Methyl-2-propanyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;3-hydroxy-8-aza-bicyclo[3.2.1]octane-8-carboxylic acid, tert-butyl ester;8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-hydroxy-,1,1-dimethylethyl ester
• CAS NO: 478837-18-2
• Molecular Formula: C₁₂H₂₁NO₃
• Molecular Weight: 227.30004
• EINECS: -0
• Mol File: 478837-18-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate(478837-18-2)
• EPA Substance Registry System: tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate(478837-18-2)

Safety Data

• Hazardous Substances Data: 478837-18-2(Hazardous Substances Data)

Usage

General Description

Tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate is a chemical compound with a complex molecular structure. It contains a ter-butyl group, a hydroxy group, and a carboxylate group, as well as a unique bicyclic structure with a nitrogen atom. tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate may have potential applications in the pharmaceutical or chemical industries due to its complex structure and potential biological activity. Further research and testing may be needed to fully understand the properties and potential uses of this chemical.

Upstream product

• 7432-11-3 8-azabicyclo[3.2.1]octan-3-ol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 25602-68-0 3-oxo-8-azabicyclo[3.2.1]octane hydrochloride 
• 185099-67-6 Boc-tropinone 

Downstream Products

• 1211875-54-5 3-phenoxy-8-azabicyclo[3.2.1]octane 
• 130753-13-8 benzyl 3-oxo-8-azabicyclo[3,2,1]octane-8-carboxylate 
• 5632-84-8 nortropinone 
• 185099-67-6 Boc-tropinone 
• 856900-26-0 3-cyano-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester 

Relevant articles and documents

Protein degradation targeting chimera for degrading androgen receptor

The invention relates to a novel difunctional molecule compound based on VHL ligand induction and application of the difunctional molecule compound in synthesis of the compounds and pharmaceutical compositions thereof. The compound is shown as a formula I. The compound can selectively induce AR protein degradation and can be used for treating cancers such as prostatic cancer and breast cancer.

Compound and application thereof

The invention provides a novel compound. The novel compound has certain inhibitory activity for indoleamine 2,3-dioxygenase (IDO) which is oxido-reductase, and accordingly the novel compound can be used for treating diseases related to the indoleamine 2,3-dioxygenase and can be applied to cancer and immunity related diseases.

BENZOXAZEPINES AS INHIBITORS OF P13K/MTOR AND METHODS OF THEIR USE AND MANUFACTURE

The invention is directed to Compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds. 9936396.1