85696-93-1

Upstream product

• 5192-23-4 4-amino-1H-indole 
• 2258-42-6 formyl acetic anhydride 

Downstream Products

• 160255-57-2 (S)-2-[(3-{2-Ethoxycarbonyl-2-[(Z)-hydroxyimino]-ethyl}-1H-indol-4-yl)-methyl-amino]-3-methyl-butyric acid benzyl ester 
• 84590-48-7 indolactam V 
• 868785-35-7 N-[1-(4-acetylamino-benzenesulfonyl)-1H-indol-4-yl]-N-methyl-acetamide 
• 160255-56-1 (S)-2-[(1H-Indol-4-yl)-methyl-amino]-3-methyl-butyric acid benzyl ester 
• 85696-95-3 1-methyl-1H-indol-4-amine 

Relevant academic research and scientific papers

Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors

An examination of several amine-substituted analogs of N 1-benzenesulfonylindoles reveals that although they bind at human 5-HT6 serotonin receptors with high affinity, they are likely to bind in a dissimilar manner.

Protein Kinase C Modulators. Indolactams. 1. Efficient and Flexible Routes for the Preparation of (-)-Indolactam V for Use in the Synthesis of Analogs

Three syntheses of the protein kinase C activator, (-)-indolactam V, are described and are compared for their potential utility in the preparation of ILV analogs.In one route the 4-amino functionality is introduced regiospecifically during the constructio

Methods for dyeing keratinous fibres with aminoindoles, compositions and devices for use

Method for dyeing keratinous fibres, in particular human keratinous fibres, such as hair, characterized in that a composition (A) containing, in a medium appropriate for dyeing, at least one aminoindole corresponding to the formula: STR1 in which: R1 and R3, independently of one another, represent a hydrogen atom or a C1 -C4 alkyl group; R2 denotes hydrogen or a C1 -C4 alkyl group or COOR', R' being a hydrogen atom or a C1 -C4 alkyl group; R4 represents a hydrogen atom or a C1 -C4 alkyl, C1 -C4 hydroxyalkyl or C2 -C4 polyhydroxyalkyl group; Z1 represents a hydrogen or halogen atom or a C1 -C4 alkyl group or OR; R being a hydrogen atom or a C1 -C4 alkyl group; and Z2 represents a hydrogen atom or a C1 -C4 alkyl group; and its salts is applied to said fibres, the colour being developed with the aid of an oxidizing system.

An Unexpected Rearrangement of 4-Alkylaminoindoles

4-Alkylaminoindoles rearrange in good yield to the corresponding 1-alkyl-4-aminoindoles in the presence of 10 molpercent hydrated toluene-p-sulphonic acid in boiling toluene.