856972-91-3Relevant articles and documents
3,5-bis(aminopyrimidinyl)indole derivatives: Synthesis and evaluation of pim kinase inhibitory activities
Lee, Jinho,More, Kunal N.,Yang, Seun-Ah,Hong, Victor S
, p. 2123 - 2129 (2014/09/16)
Pim kinases are promising targets in the treatment of hematopoietic and solid cancers. Meridianin C was chosen as a starting point to discover novel pim kinase inhibitors. Using known pim kinase's structural information, aminopyrimidine was introduced to