857066-83-2

Upstream product

• 4397-53-9 p-benzyloxybenzaldehyde 
• 857066-80-9 (R)-3-(4-hydroxy-phenyl)-2-methoxy-propionic acid sodium salt 
• 75-75-2 methanesulfonic acid 

Downstream Products

• 857066-84-3 (R)-3-(4-tert-butoxycarbonylmethoxy-phenyl)-2-methoxy-propionic acid methyl ester 
• 857066-80-9 (R)-3-(4-hydroxy-phenyl)-2-methoxy-propionic acid sodium salt 

Relevant academic research and scientific papers

An asymmetric synthesis of PPAR-γ agonist navaglitazar from (+)-methyl (2S,3R)-3-(4-methoxyphenyl)glycidate

An asymmetric synthesis of navaglitazar, a peroxisome proliferator activated receptor (PPAR) γ agonist, from commercially available (+)-methyl (2S,3R)-3-(4-methoxyphenyl)glycidate, is described. The new synthesis features high overall yield, low solvent usage, crystalline intermediates and operational simplicity. Schweizerische Chemische Gesellschaft.

SELECTIVE PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS

The present invention is directed to a novel compound, its composition and use of a compound having a structural formula (I), or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomers thereof, which is useful in treating or preventing disor