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857080-08-1

D-2-{4'-[(benzofuran-2-carbonyl)methylamino]biphenyl-4-sulfonylamino}-3-methylbutyric acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 857080-08-1 Structure

  • Basic information

    1. Product Name: D-2-{4'-[(benzofuran-2-carbonyl)methylamino]biphenyl-4-sulfonylamino}-3-methylbutyric acid tert-butyl ester
    2. Synonyms: D-2-{4'-[(benzofuran-2-carbonyl)methylamino]biphenyl-4-sulfonylamino}-3-methylbutyric acid tert-butyl ester
    3. CAS NO:857080-08-1
    4. Molecular Formula:
    5. Molecular Weight: 562.687
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 857080-08-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: D-2-{4'-[(benzofuran-2-carbonyl)methylamino]biphenyl-4-sulfonylamino}-3-methylbutyric acid tert-butyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: D-2-{4'-[(benzofuran-2-carbonyl)methylamino]biphenyl-4-sulfonylamino}-3-methylbutyric acid tert-butyl ester(857080-08-1)
    11. EPA Substance Registry System: D-2-{4'-[(benzofuran-2-carbonyl)methylamino]biphenyl-4-sulfonylamino}-3-methylbutyric acid tert-butyl ester(857080-08-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 857080-08-1(Hazardous Substances Data)

857080-08-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 857080-08-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,0,8 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 857080-08:
(8*8)+(7*5)+(6*7)+(5*0)+(4*8)+(3*0)+(2*0)+(1*8)=181
181 % 10 = 1
So 857080-08-1 is a valid CAS Registry Number.

857080-08-1Downstream Products

857080-08-1Relevant articles and documents

Biaryl sulfonamides and methods for using same

-

Page/Page column 55, (2010/02/12)

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Hu, Yonghan,Xiang, Jason S.,DiGrandi, Martin J.,Du, Xuemei,Ipek, Manus,Laakso, Leif M.,Li, Jianchang,Li, Wei,Rush, Thomas S.,Schmid, Jean,Skotnicki, Jerauld S.,Tam, Steve,Thomason, Jennifer R.,Wang, Qin,Levin, Jeremy I.

, p. 6629 - 6644 (2007/10/03)

Modification of α-biphenylsulfonamidocarboxylic acids led to potent and selective MMP-13 inhibitors. Compound 16 showed 100% oral bioavailability in rats and demonstrated >50% inhibition of bovine cartilage degradation at 10 ng/mL.

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