85725-63-9Relevant academic research and scientific papers
Base-induced Cyclization of N--2-bromo-3-hydroxybutyramide Derivatives
Shiozaki, Masao,Ishida, Noboru,Hiraoka, Tetsuo,Maruyama, Hiroshi
, p. 2135 - 2139 (2007/10/02)
Treatment of (2R,3R)-N-(2,4-dimethoxybenzyl)-N--2-bromo-3-hydroxybutyramide (5) with DBU yielded the bicyclic β-lactam 13 by a direct cyclization, and its diastereoisomer 14 and the γ-lactam 15 via the trans-epoxide 6.The same t
BASE-INDUCED CYCLIZATION OF (2R,3R)- AND (2S,3R)-N-2,4-DIMETHOXYBENZYL-N-BIS(ETHOXYCARBONYL)METHYL-2-BROMO-3-HYDROXYBUTYLAMIDE
Shiozaki, Masao,Ishida, Noboru,Hiraoka, Tetsuo,Maruyama, Hiroshi
, p. 169 - 172 (2007/10/02)
Reaction of (2R,3R)-N-2,4-dimethoxybenzyl-N-bis(ethoxycarbonyl)methyl-2-bromo-3-hydroxybutylamide (6) with DBU yielded bicyclic β-lactam 7 by a direct cyclization, and its diastereomer 8 and unexpected γ-lactam 9 by another non-direct cyclization.Also (2S
