857264-92-7Relevant academic research and scientific papers
Aminopyrimidine Derivatives With Tie2 Inhibiting Activity
-
Page/Page column 34, (2008/12/07)
The invention relates to a compound of the Formula I or salt thereof wherein Rx, Ry, Rx, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm blooded animal. The invention also relates to processes for the preparation of said compounds.
PYRIMIDINE COMPOUNDS HAVING TIES (TEK) INHIBITORY ACTIVITY
-
Page/Page column 82, (2008/06/13)
The invention relates to a compound of the Formula (I) or salt thereof wherein Rx, Ry, Rz, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm blooded animal. The invention also relates to processes for the preparation of said compounds.
PYRIMIDINE COMPOUNDS HAVING TIE2 (TEK) INHIBITORY ACTIVITY
-
Page/Page column 86, (2008/06/13)
The invention relates to a compound of the Formula (I) or salt, prodrug or solvate thereof, wherein Rx, Ry, Rz, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates t
PYRIMIDINES WITH TIE2 (TEK) ACTIVITY
-
Page/Page column 93-94, (2010/02/12)
The invention relates to a compound of the Formula (I). or salt thereof wherein R1, R2, R3, R4, R5, R6, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm-blooded animal. The invention also relates to processes for the preparation of said compounds.
