857273-77-9

Basic information

• Product Name: [2-(2-methoxyphenyl)ethoxy]acetic acid
• Synonyms: [2-(2-methoxyphenyl)ethoxy]acetic acid
• CAS NO: 857273-77-9
• Molecular Weight: 210.23
• Mol File: 857273-77-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [2-(2-methoxyphenyl)ethoxy]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(2-methoxyphenyl)ethoxy]acetic acid(857273-77-9)
• EPA Substance Registry System: [2-(2-methoxyphenyl)ethoxy]acetic acid(857273-77-9)

Safety Data

• Hazardous Substances Data: 857273-77-9(Hazardous Substances Data)

Upstream product

• 7417-18-7 2-methoxyphenethyl alcohol 
• 79-11-8 chloroacetic acid 

Downstream Products

• 857273-76-8 2-[2-(2-methoxyphenyl)ethoxy]ethanol 

Relevant articles and documents

Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: Optimization of in vitro activity

Pyrido pyrimidinones are selective agonists of the human high affinity niacin receptor GPR109A (HM74A). They show no activity on the highly homologous low affinity receptor GPR109B (HM74). Starting from a high throughput screening hit the in vitro activity of the pyrido pyrimidinones was significantly improved providing lead compounds suitable for further optimization.

ORGANIC COMPOUNDS

Novel substituted piperidines of the general formulae (I) and (II) with the substituent definitions as explained in detail in the description are described. The compounds are suitable in particular as renin inhibitors and are highly potent.