857280-01-4

Upstream product

• 40879-42-3 2-hydroxypropane-1,3-diyl bis(4-methylbenzenesulfonate) 
• 98-59-9 p-toluenesulfonyl chloride 
• 428-63-7 2,2-difluoropropane-1,3-diol 

Downstream Products

• 1311369-17-1 diethyl 1-(2,2-difluoro-3-{[(4-methylphenyl)sulfonyl]oxy}propyl)-1H-indole-2,6-dicarboxylate 

Relevant academic research and scientific papers

6,7-DIHYDRO-5H-PYRAZOLO[5,1-B][1,3]OXAZINE-2-CARBOXAMIDE COMPOUNDS

The present invention is directed to PDE4B inhibitors of Formula I: (I) or a pharmaceutically acceptable salt thereof, wherein the substituents R1, R2, R 3, and R 4are as defined herein. The invention is also di

HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE

Disclosed are novel compounds which inhibit RSK, methods of making such compounds and pharmaceutical compositions comprising such compounds. Also disclosed are methods of treating RSK2 regulated disorders using compounds of the invention.