85748-43-2Relevant academic research and scientific papers
Palladium complexes of 2-benzoylpyridine thiosemicarbazone and synthesis method thereof
-
Paragraph 0011; 0034; 0036-0039, (2020/02/14)
The invention discloses palladium complexes of 2-benzoylpyridine thiosemicarbazone and a synthesis method of the palladium complexes. The method comprises the following steps: respectively mixing andreacting 2-benzoylpyridine with 4,4-dimethyl-3-thiosemicarbazone and 3-pyrrole-3-thiosemicarbazone to prepare a ligand; and reacting the prepared ligand with PdCl2 to obtain the palladium complexes C1and C2. In-vitro proliferation inhibition activity experiments are further carried out on the synthesized palladium complexes C1-C2, and the results show that the synthesized palladium complexes havegenerally good in-vitro activity, show good inhibition activity, have little toxic effect on human normal cells, and are suitable for preparing high-efficiency and low-toxicity anti-tumor drugs.
Platinum complex taking 2-benzoylpyridine thiosemicarbazone as ligand as well as synthesis method and application of platinum complex
-
Paragraph 0051-0054, (2020/12/31)
The invention discloses a thiosemicarbazone platinum complex taking 2-benzoyl pyridine as a ligand as well as a synthesis method and application of the thiosemicarbazone platinum complex. 2-benzoyl pyridine and thiosemicarbazone are selected for condensat
