85750-24-9 Usage
Uses
Used in Pharmaceutical Industry:
alpha-(4-bromophenyl)pyridine-2-acetonitrile is used as a key intermediate in the synthesis of Bromopheniramine Maleate, a derivative of Pheniramine (P297200). Bromopheniramine Maleate is a medication utilized for the treatment of allergic conditions such as hay fever or urticaria. Its role in the synthesis process is vital for producing an effective and widely used antihistamine drug, contributing to the management and relief of allergy symptoms in patients.
Check Digit Verification of cas no
The CAS Registry Mumber 85750-24-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,7,5 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 85750-24:
(7*8)+(6*5)+(5*7)+(4*5)+(3*0)+(2*2)+(1*4)=149
149 % 10 = 9
So 85750-24-9 is a valid CAS Registry Number.
85750-24-9Relevant academic research and scientific papers
Synthesis of Primary ω-Phenyl-ω-pyridylalkylamines
Buschauer, Armin
, p. 165 - 171 (2007/10/02)
Phthalimidoalkylation of phenylpyridylacetonitriles followed by acidic or basic hydrolysis and decarboxylation is a convenient method for the preparation of pheniramine-like primary amines.Substituted dihydropyrrolamines were isolated as intermediates in the synthesis of the corresponding propylamines.Alternatively, 3,3-diarylpropylamines were prepared via Horner-Emmons reaction of pertinent ketones with diethyl cyanomethanephosphonate followed by reduction with complex hydrides.
