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857532-23-1

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857532-23-1 Usage

Molecular structure

A complex structure derived from piperidinecarboxylic acid.

Ester form

Potential candidate for use in pharmaceuticals or research applications.

Bromophenyl and chlorophenyl groups

Suggest potential in the field of medicinal chemistry.

1,1-Dimethylethyl ester group

Makes the molecule lipophilic, potentially increasing bioavailability and cellular uptake.

Further research needed

To determine specific applications and potential biological activities.

Check Digit Verification of cas no

The CAS Registry Mumber 857532-23-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,5,3 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 857532-23:
(8*8)+(7*5)+(6*7)+(5*5)+(4*3)+(3*2)+(2*2)+(1*3)=191
191 % 10 = 1
So 857532-23-1 is a valid CAS Registry Number.

857532-23-1Relevant articles and documents

5H-CYCLOPENTA[D]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS

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Page/Page column 60, (2009/09/04)

Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I).

PHARMACEUTICAL COMPOUNDS

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, (2008/06/13)

Compounds of the formula (I), and salts, solvates, tautomers and N-oxide thereof; wherein TG is selected from groups (1) and (2): wherein the asterisk (*) represents the point of attachment of the group E to the group X; Rla is an optionally substituted aryl or heteroaryl group; Rlb is hydrogen or a group Rla; X is an optionally substituted bicyclic heterocyclic group having 8 to 12 ring members of which up to 5 are heteroatoms selected from O, N and S; and A, E, R2, R3, R4, Q1 and Q2 are as defined in the claims; provided that when E is aryl or heteroaryl, then Q2 is other than a bond; and further provided that the moiety (a) is other than a group (BG1) or (BG2); wherein (BGl) and (BG2) are each optionally substituted; T is N or CRZ; J1-J2 is selected from N=C(RZ), (RZ)C=N, (RZ)N-C(O), (RZ)2C-C(O), N=N and (RZ)C=C(R6); J4 -J3 is a group N=C(RZ) or a group (RZ)N-CO; and RZ is hydrogen or a substituent. The compounds of the formula (I) have PKA and PKB kinase inhibiting activity and are useful in the treatment of cancers.

HETEROCYCLIC CONTAINING AMINES AS KINASE B INHIBITORS

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, (2010/11/25)

The invention provides a compound of the formula (I) or a salt, solvate, tautomer or N-oxide thereof; for use as a PKB kinase inhibitor or PKA kinase inhibitor. In formula (I), A is a saturated hydrocarbon linker group; E is a monocyclic or bicyclic carbo

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