857544-00-4

Upstream product

• 56245-07-9 2-(4-methoxy-3-nitrophenyl)acetonitrile 
• 6378-19-4 4-methoxy-3-nitrobenzyl chloride 
• 63367-09-9 (4-hydroxy-3-nitro-phenyl)-acetic acid amide 
• 74-88-4 methyl iodide 
• 104-01-8 4-Methoxyphenylacetic acid 
• 156-38-7 4-hydroxyphenylacetate 
• 10463-20-4 4-hydroxy-3-nitrophenylacetic acid 
• 34837-88-2 methyl 2-(4-methoxy-3-nitrophenyl)acetate 
• 63304-80-3 (4-methoxy-3-nitrophenyl)acetic acid 

Downstream Products

• 858855-65-9 2-(4-methoxy-3-nitrophenyl)ethane-1-amine 
• 1377582-09-6 2-(4-methoxy-3-thioureido-phenyl)-acetamide 
• 1377582-08-5 2-(3-isothiocyanato-4-methoxy-phenyl)-acetamide 
• 63304-81-4 2-(3-amino-4-methoxyphenyl)acetic acid 
• 63304-80-3 (4-methoxy-3-nitrophenyl)acetic acid 

Relevant academic research and scientific papers

COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING NASH, NAFLD, AND OBESITY

The present technology relates to methods of treating NASH, NAFLD and/or obesity using compounds of Formulas I, II, III, IV, V, and/or VI. The methods include administering to a subject suffering from one or more of non-alcoholic steatohepatitis (NASH), non- alcoholic fatty liver disease (NAFLD) and/or obesity a therapeutically effective amount of such a compound

PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS

The present invention discloses a pyrazole-oxazolidinone compound having anti-hepatitis B virus activity, which has the structure of formula (I), wherein each variable is as defined herein.

PYRIDYL-THIAZOLYL INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to thiazole I and its therapeutic and prophylactic uses, wherein the variables Rz, Q, J, R1, R3, R5, and R6 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.

BISTHIAZOLE INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to bisthiazole I and its therapeutic and prophylactic uses, wherein the variables A, R5, R6, and R7 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.

Compounds and Compositions for Modulating Lipid Levels and Methods of Preparing Same

The present technology relates to compounds of Formulas I-VI and methods of making and using such compounds. Methods of use include prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Compounds disclosed herein also increase HDL-C, lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression, inhibit PCSK9 expression, and activate AMP-activated protein kinase.

CORYDALINE DERIVATIVES USEFUL FOR REDUCING LIPID LEVELS

The present technology relates to compounds of Formulas (V) and (VI) and methods of making and using such compounds. Methods of use include prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Compounds disclosed herein also lower total cholesterol, LDL- cholesterol, and triglycerides and increase hepatic LDL receptor expression, inhibit PCSK9 expression, and activate AMP-activated potein kinase.