857653-96-4

Usage

Type of compound

Tertiary ester

Parent compound

Piperidinecarboxylic acid

Derivative group

4-(2-amino-2-oxoethoxy)

Substituent

1,1-dimethylethyl ester

Common uses

Building block in the synthesis of pharmaceutical compounds and agrochemicals

Potential properties

Biological activity, therapeutic effects

Application

Production of various medical and chemical products

Safety concerns

Health and environmental hazards if mishandled

Precautions

Handle with care and follow safety protocols

Upstream product

• 161948-70-5 4-(carboxymethoxy)piperidine-1-carboxylic acid tert-butyl ester 
• 543-27-1 isobutyl chloroformate 
• 189889-45-0 4-(ethoxycarbonylmethoxy)piperidine-1-carboxylic acid tert-butylester 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 442126-36-5 tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate 
• 857653-97-5 4-cyanomethoxypiperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same. The compounds include an IRAK binding moiety and a degradation inducing moiety (DIM). The DIM could be DTM a ligase binding moiety (LBM) or lysine mimetic. The compounds could be useful as IRAK protein kinase inhibitors and applied to IRAK mediated disorders.

GPCR AGONISTS

Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.

GPCR AGONISTS

Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.

G-PROTEIN COUPLED RECEPTOR AGONISTS

Compounds of Formula (I) or pharmaceutically acceptable salts or N-oxides thereof, are agonists of GPR116 and are useful for the treatment of obesity, and for the treatment of diabetes.

HETEROCYCLIC DERIVATIVES AS GPCR RECEPTOR AGONISTS

Compounds of Formula (I), R1-A-V-B-R2; or pharmaceutically acceptable salts thereof, are agonists of GPR116 and are useful as regulators of satiety, e.g. for the treatment of obesity, and for the treatment of diabetes.