857663-89-9 Usage
Structure
Contains a furan ring with a pyridine ring attached to it
Functional Groups
Carbonitrile group (-C≡N), amino group (-NH2)
Biological Activity
Potential due to the presence of the pyridine ring, a common motif in biologically active compounds
Application
Used in pharmaceutical research as a building block for synthesizing potential drug candidates
Value
Valuable target for further investigation and study in medicinal chemistry due to its chemical properties and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 857663-89-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,6,6 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 857663-89:
(8*8)+(7*5)+(6*7)+(5*6)+(4*6)+(3*3)+(2*8)+(1*9)=229
229 % 10 = 9
So 857663-89-9 is a valid CAS Registry Number.
857663-89-9Relevant academic research and scientific papers
NOVEL CHEMICAL COMPOUNDS
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Page/Page column 30, (2010/02/12)
The present invention relates generally to inhibitors of the kinases, such as GSK-3, and more particularly to fused pyrimidine compounds.
4-Acylamino-6-arylfuro[2,3-d]pyrimidines: Potent and selective glycogen synthase kinase-3 inhibitors
Maeda, Yutaka,Nakano, Masato,Sato, Hideyuki,Miyazaki, Yasushi,Schweiker, Stephanie L.,Smith, Jeffery L.,Truesdale, Anne T.
, p. 3907 - 3911 (2007/10/03)
Modeling studies of a furo[2,3-d]pyrimidine GSK-3 hit compound 1 superimposed onto the X-ray crystal structure of a legacy pyrazolo[3,4-c] pyridazine GSK-3 inhibitor 2 led to the identification of 4-acylamino-6- arylfuro[2,3-d]pyrimidine template 3. Synth
