6221-12-1

Basic information

• Product Name: 3-(2-bromoacetyl)pyridine
• Synonyms: 3-(2-bromoacetyl)pyridine;1-bromo-2(pyridin-3-yl)-2-ethanone;Ethanone, 2-broMo-1-(3-pyridinyl)-;3-(2-Bromoacetyl)
• CAS NO: 6221-12-1
• Molecular Formula: C₇H₆BrNO
• Molecular Weight: 200.03
• Mol File: 6221-12-1.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-(2-bromoacetyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-bromoacetyl)pyridine(6221-12-1)
• EPA Substance Registry System: 3-(2-bromoacetyl)pyridine(6221-12-1)

Safety Data

• Hazardous Substances Data: 6221-12-1(Hazardous Substances Data)

Usage

General Description

3-(2-bromoacetyl)pyridine is a chemical compound that consists of a pyridine ring with a bromoacetyl group attached to it at the 3-position. It is a yellow crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The bromoacetyl group imparts reactivity to the molecule, allowing it to participate in various organic reactions such as nucleophilic substitution and condensation reactions. Its versatile reactivity and the presence of the pyridine ring make 3-(2-bromoacetyl)pyridine a valuable building block for the synthesis of complex organic molecules. Additionally, the compound can also be used as a reagent for the functionalization and modification of other organic molecules.

Upstream product

• 350-03-8 methyl-3-pyridylketone 
• 21970-14-9 pyridin-3-ylmagnesium bromide 
• 108-24-7 acetic anhydride 
• 60-29-7 diethyl ether 
• 6283-81-4 3-oxo-3-pyridin-3-yl-propionic acid ethyl ester 
• 39972-50-4 2-diazo-1-(pyridine-3-yl)ethan-1-one 

Downstream Products

• 857663-88-8 2-(2-oxo-2-pyridin-3-yl-ethyl)-malononitrile 
• 944937-03-5 C₁₆H₁₈N₂O₂ 
• 391906-07-3 (1R)-2-bromo-1-(3-pyridinyl)-1-ethanol 
• 30235-27-9 4-(pyridin-3-yl)thiazol-2-amine 
• 30162-42-6 2-(3-Pyridyl)amino-4-(3-pyridyl)thiazol 
• 690616-03-6 3-[2-(4,4'-dimethoxy-benzhydryl)-thiazol-4-yl]-pyridine 
• 4192-31-8 4-oxo-4-(pyridin-3-yl)butanoic acid 
• 51746-85-1 3-(1H-imidazol-4-yl)pyridine 
• 30510-18-0 nicotinoylacetonitrile 
• 92990-44-8 2-amino-1-(pyridine-3-yl)ethanol 

Relevant articles and documents

Antiangiogenic and growth inhibitory effects of synthetic novel 1, 5-diphenyl-1,4 pentadiene-3-one-3-yl-ethanone pyridine curcumin analogues on Ehrlich ascites tumor in vivo

In the present investigation we have synthesized novel substituted dienone pyridine ethanone curcumin analogues 3a and 3b by nucleophilic substitution reactions with 2-bromo-1-pyridine-3-yl ethanone and characterized by 1H nuclear magnetic reso

Synthesis, computational studies and antioxidant activity of some 3-(2-alkylamino-4-aminothiazole-5-oyl)pyridines

A series of thiazoloylpyridine derivatives has been synthesized and analyzed to confirm the structure of the product using IR,1H and13C NMR, mass spectra and analytical data. Optimized structural and electronic parameters of all the compounds have been calculated by using B3LYP/6-31G basis set. The Mulliken charges of all atoms have been evaluated. The calculated IR spectrum has been analyzed by comparing the experimental IR. All the synthesized compounds have been examined for antioxidant activities. The antioxidant activity of 3-(2-alkylamino-4-aminothiazol -5-oyl)pyridines have been analyzed using DPPH radical scavenging assay. The compounds 6a and 6b possess higher radical scavenging activity.

DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT

Provided are a dyeing composition which contains an azo coloring agent represented by Formula 1 or 2, a dyed product which is obtained by being dyed with the dyeing composition, and a novel azo coloring agent. In Formulae 1 and 2, C1 represents a heteroaromatic group, A1 and B1 each independently represent a heteroaromatic group, an aromatic group, or a group having a methine structure, and at least one of A1 or B1 represents a heteroaromatic group, D1 represents an anthraquinonyl group, and E1 represents a heteroaromatic group, an aromatic group, or a group having a methine structure. [in-line-formulae]A1-N═N—C1—N═N—B1??Formula 1[/in-line-formulae] [in-line-formulae]D1-N═N-E1??Formula 2[/in-line-formulae]

COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY

The present invention provides novel compounds of Formula (I) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases, e.g., cancers (e.g., breast cancer, prostate cancer, lymphoma, lung cancer, pancreatic cancer, ovarian cancer, neuroblastoma, or colorectal cancer), benign neoplasms, angiogenesis, inflammatory diseases, fibrosis (e.g., polycystic kidney disease), autoinflammatory diseases, and autoimmune diseases in a subject.