857732-40-2Relevant academic research and scientific papers
Enantiospecific synthesis of (-)-trachyspic acid
Zammit, Steven C.,White, Jonathan M.,Rizzacasa, Mark A.
, p. 2073 - 2074 (2005)
The enantiospecific synthesis of (-)-trachyspic acid is presented. The D-oxyribose derived alcohol was oxidized in one step to the acid and esterification with allyl alcohol provided ester. Alkylation of the anion derived from dimethyl malonate with nonyl
Enantiospecific total synthesis of the squalene synthase inhibitors (-)-CJ-13,982 and its enantiomer from a common intermediate
Sturgess, Dayna,Chen, Zongjia,White, Jonathan M.,Rizzacasa, Mark A.
, p. 234 - 239 (2018/03/21)
The total syntheses of both the natural and unnatural enantiomers of the alkyl citrate natural product CJ-13,982 (1) from the common d-ribose-derived acid 6 are described.
