85812-92-6

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 24324-17-2 9-Fluorenylmethanol 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 

Downstream Products

• 887476-51-9 2-[(5-chloro-1-methoxymethoxy-1H-pyrrole-2-carbonyl)-amino]-3-phenyl-propionic acid 9H-fluoren-9-ylmethyl ester 
• 887476-49-5 2-[(5-chloro-1-hydroxy-1H-pyrrole-2-carbonyl)-amino]-3-phenyl-propionic acid 9H-fluoren-9-ylmethyl ester 
• 887476-52-0 2-[(5-chloro-1-hydroxy-1H-pyrrole-2-carbonyl)-amino]-3-phenyl-propionic acid 

Relevant academic research and scientific papers

Hierarchical self-assembly of di-, tri- and tetraphenylalanine peptides capped with two fluorenyl functionalities: From polymorphs to dendrites

Homopeptides with 2, 3 and 4 phenylalanine (Phe) residues and capped with fluorenylmethoxycarbonyl and fluorenylmethyl esters at the N-terminus and C-terminus, respectively, have been synthesized to examine their self-assembly capabilities. Depending on t

Synthesis of 9-fluorenylmethyl esters using 9- fluorenylmethylchloroformate

9-Fluorenylmethyl esters of amino acids were synthesized by reacting 9- fluorenylmethylchloroformate with N-protected amino acids in the presence of diisopropylethylamine (DIPEA) as base and 4-dimethylaminopyridine (DMAP) as catalyst.

9-FLUORENYLMETHYL ESTERS AS CARBOXYL PROTECTING GROUP

The use of 9-fluorenylmethyl esters for the protection of carboxyl groups is proposed.The advantage of this group is the selective deprotection under mild conditions using secondary amines without racemization.

A novel, one-pot reductive alkylation of amines by S-ethyl thioesters mediated by triethylsilane and sodium triacetoxyborohydride in the presence of palladium on carbon

The reductive alkylation of primary amines with aldehydes or ketones is an important tool in the synthesis of wide variety of amines. We described here a novel, one-pot reductive alkylation method using multifunctional S- ethyl thioesters as a source for