858120-63-5

Upstream product

• 100-44-7 benzyl chloride 
• 36106-34-0 4-(2-dimethylamino-vinyl)-nicotinonitrile 
• 5444-01-9 3-cyano-4-methylpyridine 
• 67988-50-5 2,7-naphthyridinyl-1(2H)-one 

Relevant academic research and scientific papers

PYRIDINE DERIVATIVES, METHODS OF THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

The present invention relates to pyridine derivatives having inhibitory effects on synthesis of cytokines, which are involved in inflammatory reactions, thus being useful as a therapeutic agent for treatment of inflammation-related diseases, immune-related diseases and chronic inflammatory diseases methods as well as an anti-inflammatory and analgesic agent, methods for their preparations, and pharmaceutical compositions containing the same.

NOVEL PYRIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

This invention relates to novel pyridine derivatives having an inhibitory effect on production of cytokines, which are involved in inflammatory responses, thus suggesting its usefulness as therapeutic agents for treating diseases related to inflammation, immune, chronic inflammation as well as an agent having an anti-inflammatory and analgesic effect. Further, this invention relates to a method of manufacturing the same and a pharmaceutical composition containing the same.