858124-18-2

Upstream product

• 122136-03-2 ethyl 3-formyl-4-methoxybenzoate 
• 1530-39-8 (4-chlorobenzyl)triphenylphosphonium chloride 
• 1360060-07-6 ethyl 3-[2-(4-chlorophenyl)vinyl]-4-methoxybenzoate 
• 858124-17-1 ethyl (E)-3-[2-(4-chlorophenyl)vinyl]-4-methoxybenzoate 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 82304-99-2 3-formyl-4-hydroxybenzoic acid ethyl ester 
• 39225-17-7 diethyl 4-chlorobenzylphosphonate 

Downstream Products

• 1374791-85-1 3-[(E)-2-(4-chlorophenyl)vinyl]-4-methoxy-benzoyl chloride 
• 1360060-82-7 3-[(E)-2-(4-chlorophenyl)vinyl]-4-methoxy-N,Ndimethylbenzamide 

Relevant academic research and scientific papers

CARBOXAMIDE AND SULFONAMIDE DERIVATIVES USEFUL AS TEAD MODULATORS

The invention is concerned with the compounds of formula (I) and formula (II): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of using the compounds of formula (I) and formula (II) as well as pharmaceutical compositions containing such compounds. The compounds are useful in treating diseases and conditions mediated by TEAD, such as cancer.

Angiogenesis inhibitors identified by cell-based high-throughput screening: Synthesis, structure-activity relationships and biological evaluation of 3-[(E)-styryl]benzamides that specifically inhibit endothelial cell proliferation

Proliferation of endothelial cells is critical for angiogenesis. We report orally available, in vivo active antiangiogenic agents which specifically inhibit endothelial cell proliferation. After identifying human umbilical vein endothelial cell (HUVEC) pr

BENZAMIDE DERIVATIVE

To provide compounds which have high angiogenesis inhibiting activity, and are useful as agents for effective treatment and prevention of diseases involving pathologic angiogenesis, for example, cancer and cancer metastasis, methods for producing the comp