858131-66-5Relevant articles and documents
Piperazine-2,3-dicarboxylic acid derivatives as dual antagonists of NMDA and GluK1-containing kainate receptors
Irvine, Mark W.,Costa, Blaise M.,Dlaboga, Daniel,Culley, Georgia R.,Hulse, Richard,Scholefield, Caroline L.,Atlason, Palmi,Fang, Guangyu,Eaves, Richard,Morley, Richard,Mayo-Martin, Maria B.,Amici, Mascia,Bortolotto, Zuner A.,Donaldson, Lucy,Collingridge, Graham L.,Molnár, Elek,Monaghan, Daniel T.,Jane, David E.
experimental part, p. 327 - 341 (2012/03/11)
Competitive N-methyl-d-aspartate receptor (NMDAR) antagonists bind to the GluN2 subunit, of which there are four types (GluN2A-D). We report that some N1-substituted derivatives of cis-piperazine-2,3-dicarboxylic acid display improved relative
