858132-52-2Relevant academic research and scientific papers
A concise synthesis of (+)-conagenin and its isomer using chiral tricyclic iminolactones
Wang, Hai-Fei,Ma, Guo-Hua,Yang, Shao-Bo,Han, Rong-Gang,Xu, Peng-Fei
, p. 1630 - 1635 (2008/12/21)
An efficient synthesis of (+)-conagenin, a novel immunomodulator produced by Streptomyces roseosporus, has been achieved via the shortest route at present. At the same time, 2-epiconagenin was synthesized according to the same methodology.
Synthesis of an immunomodulator (+)-conagenin and its analogs
Yakura, Takayuki,Yoshimoto, Yuya,Ishida, Chisaki,Mabuchi, Shunsuke
, p. 4429 - 4438 (2008/02/02)
Stereoselective synthesis of an immunomodulator (+)-conagenin was achieved. Both amine and carboxylic acid moieties were prepared from commercially available optically active methyl 3-hydroxy-2-methylpropanoate using dirhodium(II)-catalyzed C-H amination
Stereoselective synthesis of an immunomodulator (+)-conagenin using dirhodium(II)-catalyzed C-H amination and chelation-controlled reductions as key steps
Yakura, Takayuki,Yoshimoto, Yuya,Ishida, Chisaki,Mabuchi, Shunsuke
, p. 930 - 932 (2007/10/03)
Stereoselective synthesis of an immunomodulator (+)-conagenin from commercially available optically active methyl 3-hydroxy-2-methylpropanoate was achieved using dirhodium(II)-catalyzed C-H amination and chelation-controlled reductions as key steps. Georg
Synthesis of (+)-conagenin
Matsukawa, Yohei,Isobe, Minoru,Kotsuki, Hiyoshizo,Ichikawa, Yoshiyasu
, p. 5339 - 5341 (2011/11/14)
An efficient total synthesis of (+)-conagenin was achieved. The right fragment of conagenin, α-methylserine containing a quaternary stereocenter attached to nitrogen, was synthesized using allyl cyanate-to-isocyanate rearrangement. The left fragment, 2,4-
